Notably, basal annexin V binding in T2DM patients was higher than that of control subjects, both in terms of annexin V binding positive percentages (2.3±0.4% vs 1.1±0.3%; P<0.05) and MFI (8.92±1.35 vs 5.27±0.37; P<0.05). This evidence concerns the gene ANXA5 and type 2 diabetes mellitus.