IRF3 and skin squamous cell carcinoma: Of note these occur within an ETS-like motif, within a DHS peak, within a site with multiple transcription factor ChIP-seq peaks and occur as a dinucleotide change in two samples; moreover the site is annotated within the 5′UTR of another gene, IRF3. Therefore cSCC displays the same phenomenon as demonstrated in the above cutaneous malignancies in at least two sites.