Meanwhile, EGFL7 mRNA expression was positively correlated with tumor size, TNM stage, liver cirrhosis and VEGF expression of HCC patients (all P < 0.05) (all P < 0.05), but EGFL7 mRNA expression had no associations with age, gender, PVTT, capsular infiltration and HBsAg (all P > 0.05). The gene discussed is VEGFA; the disease is cirrhosis of liver.