Subsequently, spinal cord changes at 49 dpi were further evaluated on a molecular level showing that IL-6 mRNA transcription was significantly decreased in IL-10R blocked mice (group “IL-10R↓late/TMEV”) compared to isotype-treated animals following TMEV-infection (group “isotypelate/TMEV”, Fig 6, Table F in S1 File). This evidence concerns the gene IL10RA and infection.