Even though metabolic endotoxemia was previously reported in both T2DM and CAD [62, 63], in T2DM it is associated with significantly reduced levels of EndoCAb, with no apparent change in the levels of sCD14 and LBP (unpublished data) while in CAD it is associated with significantly elevated levels of EndoCAb and decreased levels of sCD14 with no change in LBP levels [61]. Here, LBP is linked to coronary artery disorder.