Expression of numerous ion channels such as sodium channel NaV1.5 (de la Rosa et al., 2013), potassium channels or NaH exchanger is often implicated in arrhytmogenesis in cardiac hypertrophy and/or failure (Stevens et al., 2013) and detailed analysis at the molecular and functional level together with temporal dynamics would require numerous further experiments using alternative techniques (RT-PCR, patch clamp, isolated myocytes). Here, KCNA3 is linked to cardiac hypertrophy.