Comparative analysis of the changes in ICAM-1 (IACM-1Δ) and TNF-α (TNF-αΔ) levels between the H group and the HD groups revealed a more pronounced decrease in the HD group (ICAM-1Δ: 0.55 ± 0.64 pg/ml to 1.01 ± 0.80 pg/ml, P = 0.037; TNF-αΔ: 20.84 ± 14.89 pg/ml to 32.23 ± 14.33 pg/ml, P = 0.011, respectively, Figure 3). The gene discussed is ICAM1; the disease is Huntington disease.