The results of the present study are consistent with those of a study using an animal model, in which amlodipine plus atorvastatin significantly reduced TNF-α levels (Kawai et al., 2011; Zhang et al., 2012), and with the results of the MARGAUX study in which the said combination treatment significantly reduced the levels of adhesion molecules in human coronary disease (Charbonneau et al., 2008). The gene discussed is TNF; the disease is coronary artery disorder.