The number of DCX-positive migrating neuroblasts in the lateral ventricle area and hippocampal region of stroke-affected hemispheres significantly increased after treatment with NBE-MSC-MVs compared to that of PBS (Fig. 3A), suggesting that NBE-MSC-MVs potentially promote neurogenesis by neural stem cells in the hippocampus and SVZ, and these cells migrate toward the ischemic boundary after stroke. This evidence concerns the gene DCX and stroke disorder.