IGFBP7 and acute kidney injury: [TIMP 2]*[IGFBP7] urine concentrations in patients with KDIGO AKI 3 (median 6.49, range 1.06–8.66) were significantly higher than in patients with KDIGO AKI 0 (median 0.21, range 0.06–3.03) or KDIGO AKI 1 (median 0.35, range 0.06–0.57).