IGFBP7 and acute kidney injury: Accordingly, patients with AKI 2 or 3 showed significantly higher [TIMP 2]*[IGFBP7] urine concentrations than patients with AKI 0–1 (median 5.11, range 1.06–8.66 vs. 0.23, range 0.06–3.03, p < 0.05).