Regardless of whether adverse events were related to CPT treatment, the most common events (defined as incidence in ≥10% of patients) were AST elevation (63.0%), fever (59.3%), ALT elevation (55.6%), leucopenia (48.2%), thrombocytopenia (25.9%), neutropenia (18.5%), upper respiratory infection (18.5%), anemia (14.8%), rash (14.8%), fatigue (14.8%), hypokalemia (11.1%), lactate dehydrogenase (LDH) elevation (11.1%), pneumonia (11.1%), cough (11.1%), pharyngitis (11.1%), abdominal pain (11.1%), and diarrhea (11.1%). The gene discussed is GPT; the disease is Decreased total neutrophil count.