Puccetti et al. (2010) conducted a case–control study to explore specific genetic and/or environmental factors to statin intolerance and they found a significant association between the C allele of rs4149056 SNP in the SLCO1B1 and myopathy in atorvastatin-treated patients (OR = 2.7, 95 % CI 1.3–4.9, P < 0.001). Here, SLCO1B1 is linked to myopathy.