Forty CpG-sites exhibited differences in their methylation level between MS patients and controls, while the strongest associations were in a probe near transmembrane protein 48 (TMEM48) transcription start site, in the first exon of adenomatous polyposis coli protein 2 (APC2) and in several CpG-sites within dynein heavy chain domain 1 (DNHD1) gene [44]. This evidence concerns the gene NDC1 and myeloid sarcoma.