As increased CAMK2 mRNA expression predicts that breast cancer patients will have shorter overall and distant metastasis free survival (Fig. 1), and phosphorylation of CaMKII at T286 was significantly increased in breast cancer and lymph node metastases tissue (Fig. 2), we tested whether CaMKII overexpression or phosphorylation at T286 could alter processes known to be involved in breast cancer cell metastasis. This evidence concerns the gene CAMK2G and breast carcinoma.