For this purpose, we used the following human mammary cells: highly invasive MDA-MB-231 (oestrogen receptor [ER] and progesterone receptor [PR] negative) breast tumour cells, the minimally invasive MCF7 (ER and PR positive) breast tumour cells and MCF10A human mammary epithelial cells (ER and PR negative). Here, PGR is linked to breast neoplasm.