Another study reported that the TP53 K351N mutation may induce platinum resistance after platinum-based NACT and act as an independent risk factor for shorter disease-free survival in advanced ovarian cancer patients who underwent NACT-IDS.[18] Postoperative residual tumor mass >1 cm is another risk factor associated with higher platinum-resistant recurrence risk (adjusted OR 2.915, P = 0.000), which is consistent with Rauh-Hain's research.[19]. The gene discussed is TP53; the disease is neoplasm.