MTHFR and triple-A syndrome: Interestingly, in our previous study,[20] there was a significant association between the MTHFR 677T allele and the risk of AAA (OR = 2.46; 95% CI = 1.10–5.50; P = 0.03) in the subgroup of patients who consumed alcohol, indicating that consuming alcohol may play an important role in the association between the MTHFR C677T polymorphism and AAA.