Some reports have found no evidence that HCV infection accelerates CD4 decline and AIDS progression, nor that it compromises CD4 count recovery after initiation of cART.[23,24] Other studies have reported that HCV coinfection is associated with a higher risk of progression to AIDS[25] and poorer CD4 recovery even after several years from cART initiation.[26] Berenguer et al[27] published that the eradication of HCV in HIV/HCV-coinfected patients is associated with decreases in HIV progression and lower risks of both liver and nonliver-related mortality. Here, CD4 is linked to coinfection.