Additional adjustment for current CD4/CD8 ratio (see Table 5) led to similar conclusions with regard to the effect of low HDL-c values (AHR of any cancer for low vs normal: 1.87, 95% CI 1.14–3.06, P = 0.013; AHR of ADM for low vs normal: 1.19, 95% CI 0.56–2.52, P = 0.648; AHR of NADM for low vs normal: 2.65, 95% CI 1.38–5.08, P = 0.003] with a weak association with CD4/CD8 ratio. Here, CD8A is linked to cancer.