CD4 and cancer: Notably, the risk of cancer diagnosis was higher in patients with low current HDL-c values (adjusted HR [AHR] for low vs normal: 1.87, 95% CI 1.18–2.95, P = 0.007) and in those with older age (AHR per 5-years older: 1.32, 95% CI 1.20–1.44, P < 0.001), low current CD4 levels (AHR per 100 cells/mm3 higher: 0.78, 95% CI 0.68–0·91, P < 0.001), high current HIV-RNA values (AHR per 1 log10 copies/mL higher: 1.69, 95% CI 1.36–2·11, P < 0.001), and more recent calendar year of enrollment (AHR per 1 more recent year: 1.10, 95% CI 1.03–1.17, P = 0.005).