NFKB1 and neoplasm: Since the NF-κB1 signaling pathway is involved in the apoptosis and proliferation of tumor cells, we suspected that miR-9 may promote the proliferation of chondrocytes and suppress the apoptosis of human pituitary knee OA chondrocytes through regulating the NF-κB1 signaling pathway by targeting NF-κB1 and this is consistent with the results from the western blotting.