In 8 T-ALL patients (74, 194, 544, 636, 727, 744, 791 and 879), we identified 4 known somatic mutations (p.I314T, p.R116*, p.R225*, p.Y303*) and 2 novel mutations (p.E221*, p.G226fs) in the well-known X-linked driver gene PHF6 (Figure 3A). The gene discussed is PHF6; the disease is acute lymphoblastic leukemia.