Mouse pancreatic stellate cells (mPSC) and mouse PanIN cells from KC (LSL-KrasG12D/+; Pdx1Cre/+) mice, primary PDAC (PDA) and liver metastasis (LMP) cell lines derived from the KPC (LSL-KrasG12D/+; Trp53R172H/+; Pdx1Cre/+) mice [22] were also examined for baseline total and pSTAT3 expression (Figure 1A, right panel). Here, CALCA is linked to Patent ductus arteriosus.