The data showed that the miRNAs hsa-miR-182-5p, hsa-miR-200a-3p, hsa-miR-99a-5p, hsa-miR-100-5p, hsa-miR-145-5p, hsa-miR-214-3p may alter the transcriptional levels of several genes grouped in different pathways such as bladder cancer pathway (has05219), adherens junction pathway (hsa04520), PIK3CA-Akt signal pathway (hsa04151), MAPK signal pathway (hsa04010) and in general cancer pathways (hsa05200) (Table 4). The gene discussed is PIK3CA; the disease is cancer.