RELN and schizophrenia: The aim of the present study was to investigate whether extracellular reelin alters cell motility in schizophrenia patient-derived olfactory cells.17,24,25 Gene expression profiling of patient olfactory cells indicated that expression of many genes in the reelin signaling pathway were significantly affected in schizophrenia, including reduced RELN expression, compared with healthy control cells.24 These cells may have less intracellular reelin and be impaired in their response to extracellular reelin.