Patient cells also expressed less endogenous reelin than control cells, just as reduced reelin mRNA and protein is reported in schizophrenia-derived cells24 and post-mortem brain tissue.5–8 Reduced reelin expression in post-mortem brain tissue led to the hypothesis that neuronal migration would be impaired in the developing brain in schizophrenia.28 This is the first study to show a link between reduced reelin and functional deficits in cell migration in schizophrenia. The gene discussed is RELN; the disease is schizophrenia.