These include (1) tyrosine kinase expressed in hepatocellular carcinoma (TEC), (2) Bruton’s tyrosine kinase (BTK), (3) interleukin (IL)-2-inducible T-cell kinase (ITK), (4) tyrosine-protein kinase (TXK), and (5) bone marrow tyrosine kinase on chromosome X (BMX).[2] Tec family kinases have been the focus of immunological interest ever since their discovery. Here, BTK is linked to hepatocellular carcinoma.