While BTK, ITK and TXK show selective expression in cells of bone marrow origin,[3] the expression patterns of BMX and TEC are broader and extends to certain normal somatic cells — such as the cardiac endothelium as a response to ischemia and pressure overload.[4] Specifically, BMX is expressed in hematopoietic cells of the myeloid lineage like granulocytes and monocytes.[5,6] Besides, BMX expression has also been demonstrated in glioblastoma cancer stem cells and several solid tumors, such as prostate and breast cancer. The gene discussed is BMX; the disease is breast cancer.