Other LMNA mutations are associated with atypical progeroid syndromes, not systematically associated with progerin accumulation (Fukuchi et al., 2004; Moulson et al., 2007; Doubaj et al., 2012; Barthelemy et al., 2015) or MAD (Novelli et al., 2002). This evidence concerns the gene LMNA and progeroid syndrome.