Many of them point to specific regulatory and signaling pathways (like dopaminergic, glutamatergic, GABAergic, and cholinergic pathways, the neuregulin signaling pathway, and the Akt/GSK-3 pathway) and to specific neural mechanisms (like those involving dendritic spines and synaptic terminals, synapses, gray matter development, and neural plasticity, Buonanno, 2010; Karam et al., 2010; Bennett, 2011; Schizophrenia Working Group of the Psychiatric Genomics Consortium, 2014; Hall et al., 2015). Here, AKT1 is linked to schizophrenia.