In the present study, the proteins identified were mimecan (osteoglycine), aortic smooth muscle, Lumican, Peroxiredoxin-1, 14-3-3 protein sigma, Alpha-enolase, Keratin, type II cytoskeletal 5, as differential proteins among cervical cancer and normal cervical cells, whose expression patterns were either increased or diminished. This evidence concerns the gene ENO1 and cervical cancer.