MC4R and major depressive disorder: SNPs were classified as influential using statistical tests based on studentizedresiduals and Cook’s distance (see Materials and Methods for details).The following SNPs – rs number (gene locus) – were classified asinfluential: rs4256980 (TRIM66), rs12401738 (FUBP1), rs9925964(KAT8), rs11191560 (NT5C2), rs11057405 (CLIP1) inbipolar disorder; rs13107325 (SLC39A8), rs11191560 (NT5C2),rs9400239 (FOXO3) and rs4787491 (INO80E) in schizophrenia; andrs571312 (MC4R), rs1462433 (HNF4G), rs6785875 (FHIT) andrs11191560 (NT5C2) in major depressive disorder (Fig.2).