ANKLE1 and breast cancer: Two perfectly correlated SNPs rs61494113 and rs67397200 located between the ANKLE1 and ABHD8 genes demonstrated the strongest association with BC risk among BRCA1 mutation carriers (χ2-test P=7.8 × 10−16) and ER-negative BC in BCAC (χ2-test P=1.3 × 10−13, P-meta-analysis=7.3 × 10−28).