Furthermore, in four out of eight EATL-I tumours, JAK1 was affected by missense mutations at the same amino-acid residue G1097, a position that has been reported as frequently mutated in anaplastic large cell lymphomas27, and two harboured hotspot gain-of-function STAT3 mutations (N647I and K658N)28. The gene discussed is STAT3; the disease is neoplasm.