The acute cytokine and chemokine response to stroke in C57BL/6 mice still failed to show a significant correlation with humans when G-CSF, IL-6, and KC/IL-8 were excluded from the calculation of the R2 value (R2 = 0.0254, p = 0.5018; Fig. 4b, dotted line). This evidence concerns the gene IL6 and stroke disorder.