KAT6A and cancer: For example, the KAT6A promoter is more open specifically in MFD-1 cells (Fig. 4c, top) although at other loci, exemplified by the KRT8 gene, the chromatin associated with the TSS is more open in both MFD-1 and OE33 cancer cell lines compared to HET1A cells (Fig. 4c, bottom).