In support of COX11 and TOM1L1 being the targets of this breast cancer susceptibility locus, eQTL analyses in normal breast tissue showed borderline significant associations of the risk alleles of top candidate causal SNP rs2787486 with increased expression levels of both TOM1L1 and COX11; candidate SNP rs2787481 also showed evidence of allelic imbalance in COX11 expression. The gene discussed is COX11; the disease is breast carcinoma.