However, in TCGA multiple SNPs associate with expression of the shortest isoform of STXBP4 (uc010dcc) with the top breast cancer risk SNP, rs2787486 having a FDR corrected P = 4.0 × 10−8 (r2 = 0.06, Supplementary Figure 4). This evidence concerns the gene STXBP4 and breast cancer.