In further analyses that involved the combination of coronary heart disease, stroke, and heart failure as the outcome, improvements in C-index with NT-proBNP concentration assessment were possibly greater among older individuals and people with a history of diabetes, who used antihypertensives, who had a higher systolic blood pressure, and who had a lower total cholesterol concentration (appendix p 38). Here, NPPB is linked to coronary artery disorder.