Niemann–Pick disease type C (NP-C) is a rare neurodegenerative disease caused by autosomal recessive mutations in either the NPC1 gene (in 95 % of cases) or the NPC2 gene [1], resulting in impaired intracellular lipid trafficking and accumulation of glycolipids in various tissues including the brain [2]. This evidence concerns the gene NPC1 and nasopharyngeal carcinoma.