Mel501 melanoma cells were injected into the right flank of SCID mice and at the onset of tumor (when tumors had approximately reached 50 mm3), mice were treated with Pyr (45 mg/kg) or MBP (12 mg/kg) for 5 days per week up to 40 days from tumor injection for a total 35 days of drug administration. The gene discussed is MBP; the disease is melanoma.