Among the differential ASEs associated with viral infection, at least 10 ASEs resulted in the addition or loss of predicted nuclear localization signals (NLS) including the CDC-Like Kinase 4 (CLK4), the e2F3 transcription factor, and the Influenza Virus NS1A Binding Protein (IVNS1ABP). The gene discussed is IVNS1ABP; the disease is viral infectious disease.