In the present study, the splicing of eight of these Esrp1-regulated transcripts are also found to be differentially spliced upon viral infection (ASPH, JMJD1C, MACF1, NASP, NEDD4L, RBM39, TRA2A, WSB1) suggesting, at least in part, that some of the observed splicing alterations observed upon viral infection could be related to Esrp1 over-expression. This evidence concerns the gene ASPH and viral infectious disease.