ABCA1 and astrocytoma (excluding glioblastoma): To extend our studies beyond CCF-STTG1 astrocytoma cells (APOE3/APOE4) [22], we next verified the apoE and ABCA1 activities of compound 82879 in non-transformed primary human astrocytes from three donors genotyped as APOE3/E3 or APOE3/E4.