Recently, rare variants of genes other than SCN9a were described in patients with clinically verified erythromelalgia: those genes included SCN10A (Nav1.8), SCN11A (Nav1.9), SCN5A (Nav1.5), SCN7A (Nav2.1), SCN8A (Nav1.6), SCN1B (Nav β1 subunit), SCN3B (Nav β3 subunit), TRPA1, TRPV1, WNK1 and NGFR [8]. The gene discussed is SCN8A; the disease is erythromelalgia.