Both MIF −173 G/C promoter polymorphisms were significantly associated with AD (Table 2); the OR for CC homozygotes of the MIF −173 G/C polymorphism was 9.3 (compared to GG homozygotes, 95% CI, 1.02–84.37; p = 0.048), and the OR for GC heterozygotes of the MIF −173 G/C polymorphism was 2.5 (compared to GG homozygotes, 95% CI, 1.09–5.55, p = 0.031). Here, MIF is linked to Alzheimer disease.