SLC17A6 and Hypoglycemia: In addition, mice lacking vesicular glutamate transporter 2 (Vglut2) in SF-1 neurons exhibited a modest increase in body weight when exposed to high fat diet (HFD) and also developed hypoglycemia during fasting due to impaired induction of the glucose raising hormone glucagon and the gluconeogenic enzymes PEPCK and G6Pase [14].