CHAT and Alzheimer disease: The meta-analysis from the exclusion of Cook (1) study showed that CHAT rs2177369 mutant was not associated with AD risk in all five genetic models (allelic G versus A: OR = 0.96, 95% CI: 0.70–1.31, P = 0.78; homozygous GG versus AA: OR = 0.91, 95% CI: 0.52–1.59, P = 0.73; heterozygous GA versus AA: OR = 0.83, 95% CI: 0.62–1.10, P = 0.19; dominant GG + GA versus AA: OR = 0.87, 95% CI: 0.67–1.14, P = 0.32, statistical power = 19.62%; recessive GG versus GA + AA: OR = 1.04, 95% CI: 0.63–1.71, P = 0.88, statistical power = 5.97%) (Table 5, Figure S1).