In the immune system, GPR55 is highly expressed in the spleen and leukocytes, and its role in the modulation of innate and adaptive immune responses suggests a potential therapeutic effect for sepsis (Staton et al., 2008; Lin et al., 2011; Schicho and Storr, 2012; Stančić et al., 2015). Here, GPR55 is linked to Sepsis.