2009). These 106 genes were ontologically enriched for terms related to hormone stimulation response, apoptosis, focal adhesion, chemokine signaling pathway, cancer, VEGF signaling, cell development, and differentiation (Table 1). Many of these functional pathways have been previously associated with CRISPLD2 (Kaplan et al. 1999; Oyewumi et al. 2003a, 2003b; Nadeau et al. 2006; Quinlan et al. 2007; Lan et al. 2009; Wang et al. 2009, 2013; Shen et al. 2011; Yoo et al. 2014; Zhang et al. 2015). The complete set of differentially expressed genes is described in Table 2. This evidence concerns the gene CRISPLD2 and cancer.