ROCK1 and Insulin resistance: 2015). Interestingly, it was described that two of its targets, NRAS and ROCK1, were involved in insulin‐signaling and glucose metabolism. ROCK1 deficiency was found to induce insulin resistance by impairing insulin signaling in skeletal muscle in mice (Lee et al. 2009). ROCK1 was found to be a positive regulator of insulin action on glucose transport in adipocytes and muscle cells (Chun et al. 2012).