XPO1 and cancer: Using of six known cancer and stem cell-related signatures – chemoresistance (72 genes22), ES EXP1 (stem cell, 40 genes23), proliferation (148 genes24), NOS targets (179 genes25), MT signature (64 genes26), invasiveness (186 genes27) – to cluster the datasets in the GSA protocol yielded the same two groups seen in Fig. 2.