NR3C1 and stomach disorder: In the network, ESR1 (Estrogen Receptor) was the target with the highest degree (DD = 11), followed by NR3C1 (Glucocorticoid receptor, DD = 10), PLA2G2A (Phospholipase A2 group IIA, DD = 8), AR (Androgen Receptor, DD = 8), CYP2A6 (Cytochrome P450 2A6, DD = 7), CYP1B1 (Cytochrome P450 1B1, DD = 6) and etc. Evidence suggests that the potential active compounds in SHD can act on these targets, thus contributing to therapeutic effect on stomach diseases.