Whereas results from CD138 immunohistochemical staining showed that the positive rate of CD138 immunohistochemical staining of the 25 suspected CE patients was 12 %, the CD138 positive rate of endometrial tissue of the 68 non-chronic endometritis patients was 33.8 %, and the difference was statistically significant. The gene discussed is SDC1; the disease is chronic endometritis.