Analyses of the expression of the neural crest cell marker p75/CD271, another melanoma‐initiating cell marker (Boiko et al, 2010; Civenni et al, 2011), by Western blot and Q‐PCR, consistently revealed its upregulation in A375 and SKMEL5 cells that overexpressed ZEB1 (Fig 4A and B, Appendix Fig S3B). Here, ZEB1 is linked to melanoma.