REN and type 2 diabetes mellitus: The odds-ratio for CVD risk with increased plasma renin levels was 1.45 (95 % C.I. 1.19–1.76) for T2D subjects treated with RAAS inhibitors and 1.41 (95 % C.I. 1.04–1.93) for those not treated with RAAS inhibitors when controlling for age, gender, total cholesterol, HDL, systolic blood pressure, smoking and study center.